EPIDEMIOLOGY OF INFLUENZA IN THE ELDERLY: EVIDENCE OF VIRUS RECYCLING
Identifieur interne : 000198 ( 1968/Analysis ); précédent : 000197; suivant : 000199EPIDEMIOLOGY OF INFLUENZA IN THE ELDERLY: EVIDENCE OF VIRUS RECYCLING
Auteurs : Stephen C. Schoenbaum ; Marion T. Coleman [États-Unis] ; Walter R. Dowdle [États-Unis] ; Stephen R. Mostow [États-Unis]Source :
- American Journal of Epidemiology [ 0002-9262 ] ; 1976.
Abstract
During the Hong Kong influenza epidemic of 1968–1969 the attack rate among persons born prior to 1890 was about one-third the rate among persons born after 1899. During an Asian influenza epidemic in the same community two years earlier there was no apparent age effect. Most persons born before 1890 had detectable pre-epidemic antibody against A/Hong Kong/68 whereas most persons born after 1899 had no detectable pre-epidemic antibody. The lower attack rate in the older age group is consistent with the hypothesis that influenza A viruses with similar or identical hemagglutinins can reemerge over time and that remote previous experience with the same or a similar strain can be protective. Also, no age group born after 1890 was found to have a high prevalence of antibody against A/England/72 or A/Dunedin/73, the successors to A/Hong Kong/68, indicating that recycling of hemagglutinin antigens is not strictly ordered.
Url:
DOI: 10.1093/oxfordjournals.aje.a112214
Affiliations:
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Mostow</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Géorgie (États-Unis)</region></placeName><wicri:cityArea>Respiratory Virology Branch, Virology Division, Bureau of Laboratories, Center for Disease Control Atlanta</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">American Journal of Epidemiology</title><idno type="eISSN">1476-6256</idno><idno type="ISSN">0002-9262</idno><imprint><publisher>Oxford University Press</publisher><date when="1976-02">1976</date><biblScope unit="vol">103</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="166">166</biblScope><biblScope unit="page" to="173">173</biblScope></imprint><idno type="ISSN">0002-9262</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0002-9262</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">During the Hong Kong influenza epidemic of 1968–1969 the attack rate among persons born prior to 1890 was about one-third the rate among persons born after 1899. During an Asian influenza epidemic in the same community two years earlier there was no apparent age effect. Most persons born before 1890 had detectable pre-epidemic antibody against A/Hong Kong/68 whereas most persons born after 1899 had no detectable pre-epidemic antibody. The lower attack rate in the older age group is consistent with the hypothesis that influenza A viruses with similar or identical hemagglutinins can reemerge over time and that remote previous experience with the same or a similar strain can be protective. Also, no age group born after 1890 was found to have a high prevalence of antibody against A/England/72 or A/Dunedin/73, the successors to A/Hong Kong/68, indicating that recycling of hemagglutinin antigens is not strictly ordered.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Géorgie (États-Unis)</li></region></list><tree><noCountry><name sortKey="Schoenbaum, Stephen C" sort="Schoenbaum, Stephen C" uniqKey="Schoenbaum S" first="Stephen C." last="Schoenbaum">Stephen C. Schoenbaum</name></noCountry><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Coleman, Marion T" sort="Coleman, Marion T" uniqKey="Coleman M" first="Marion T" last="Coleman">Marion T. Coleman</name></region><name sortKey="Dowdle, Walter R" sort="Dowdle, Walter R" uniqKey="Dowdle W" first="Walter R." last="Dowdle">Walter R. Dowdle</name><name sortKey="Mostow, Stephen R" sort="Mostow, Stephen R" uniqKey="Mostow S" first="Stephen R." last="Mostow">Stephen R. Mostow</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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